|Patients on Vytorin or Zetia|
On 1/14/08, the results of a 2 year, 720 patient trial became available to the public called the ENHANCE trial. It looked at patients who have a genetic abnormality leading to LDL ("bad cholesterol") of greater than 300. The study looked at measurements of the thickness in the arteries in the neck (CIMT, a test offered in our office) and what effect simvastin had verses simvastatin and Zetia (Vytorin). This thickness and worsening of the thickness in the artery are signs that might lead to heart attacks and/or strokes. The study was not designed to see if Vytorin decreased the risk of death, heart attacks or strokes.
The study did show the following:
So what does all of this mean?
In summary, DON"T PANIC. We recommend you discuss this matter with your physician at your next appointment while contuning your medication. Feel free to make an appointment sooner if you wish to discuss this matter. Be cautious reading all the internet articles as some may not be from recognized medical sources. We have included a link to the American College of Cardiology for your review. As always, continue to improve your diet and exercise habits.